TBC1D8B（TBC1 domain family member 8B），癌症关联基因，基因ID：54885，该基因编码一个具有TBC（Tre-2/Bub2/CDC16）结构域的蛋白质一些具有此结构域的哺乳动物蛋白通过与特定rab蛋白结合并影响其gtpase活性而发挥rab间隙的功能。选择性剪接导致多个转录变体[由RefSeq提供，2011年9月]This gene encodes a protein with a TBC (Tre-2/Bub2/CDC16) domain. Some mammalian proteins with this domain have been shown to function as Rab-GAPs by binding to specific Rab proteins and affecting their GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq， Sep 2011]。