SOX4（SRY-box transcription factor 4），癌症关联基因，基因ID：6659，这个无内含子的基因编码一个SOX（SRY相关HMG-box）转录因子家族的成员，该家族参与胚胎发育的调控和细胞命运的决定编码的蛋白质在与其他蛋白质（如syndecan结合蛋白（syntenin））形成蛋白质复合物后可作为转录调节因子。该蛋白可能在细胞凋亡途径中发挥作用，导致细胞死亡和肿瘤发生，并可能在骨发育中介导甲状旁腺激素（pth）和pth相关蛋白（pthrp）的下游效应。对类似小鼠蛋白的hmg盒的溶液结构进行了解析。[由RefSeq提供，2008年7月]This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins， such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provid。