HSPA8（heat shock protein family A (Hsp70) member 8），癌症关联基因，基因ID：3312，这个基因编码热休克蛋白70家族的一个成员，它包含热诱导和组成性表达的成员。这种蛋白质属于后者，也被称为热休克同源蛋白它作为一种伴侣，与新生的多肽结合以促进正确的折叠。它还作为一种atp酶，在膜组分通过细胞运输过程中分解氯氰菊酯包被的囊泡另外，已经发现该基因编码不同亚型的剪接转录变体[由RefSeq提供，2011年8月]This gene encodes a member of the heat shock protein 70 family， which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group， which are also referred to as heat-shock cognate proteins. It functions as a chaperone， and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq， Aug 2011]。