FUS（FUS RNA binding protein），癌症关联基因，基因ID：2521，该基因编码异质核核糖核蛋白（hnrnp）复合物的多功能蛋白成分。hnRNP复合物参与mRNA的前剪接和全加工mRNA向细胞质的输出该蛋白属于FET家族的RNA结合蛋白，参与了包括基因表达调控、基因组完整性维护和mRNA/microRNA处理在内的细胞过程选择性剪接导致多个转录变体该基因缺陷导致肌萎缩侧索硬化6型[由RefSeq提供，2009年9月]This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression， maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq， Sep 2009]。