CYBA（cytochrome b-245 alpha chain），癌症关联基因，基因ID：1535，细胞色素b由轻链（α）和重链（β）组成该基因编码光，α亚基，已经提出作为吞噬细胞的杀微生物氧化酶系统的主要成分。该基因的突变与常染色体隐性遗传性慢性肉芽肿性疾病（CGD）有关，其特征在于活化的吞噬细胞的失败产生超氧化物，这对于这些细胞的杀微生物活性是重要的。[由RefSeq提供，2008年7月]Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light， alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD)， that is characterized by the failure of activated phagocytes to generate superoxide， which is important for the microbicidal activity of these cells. [provided by RefSeq， Jul 2008]。