IFNGR1（interferon gamma receptor 1），癌症关联基因，基因ID：3459，这个基因（ifngr1）编码γ干扰素受体的配体结合链（α）。人干扰素γ受体是ifngr1和ifngr2的异二聚体。ifngr1基因变异与幽门螺杆菌感染易感性有关。此外，ifngr1的缺陷是孟德尔对分枝杆菌病（也称为家族性播散性非典型分枝杆菌感染）易感性的原因。[由RefSeq提供，2008年7月]This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition， defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease， also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq， Jul 2008]。