GATA4（GATA binding protein 4），癌症关联基因，基因ID：2626，该基因编码锌指转录因子gata家族的一个成员。这个家族的成员认识到gata基序存在于许多基因的启动子中。这种蛋白被认为是调节胚胎发生、心肌分化和功能的基因，是睾丸正常发育所必需的。该基因突变与心脏间隔缺损有关。此外，基因表达的改变与几种癌症类型有关。选择性剪接导致多个转录变体。[由RefSeq提供，2015年4月]This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function， and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally， alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq， Apr 2015]。