PRKDC(protein kinase, DNA-activated, catalytic subunit),癌症关联基因,基因ID:5591,该基因编码dna依赖性蛋白激酶(dna-pk)的催化亚单位。与ku70/ku80异二聚体蛋白共同参与dna双链断裂修复和重组。编码的蛋白质是PI3/PI4激酶家族的成员。[由RefSeq提供,2010年7月]This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]。