HSPA5（heat shock protein family A (Hsp70) member 5），癌症关联基因，基因ID：3309，该基因编码的蛋白是热休克蛋白70（hsp70）家族的成员。局限于内质网（ER）内腔，参与ER中蛋白质的折叠和组装。由于这种蛋白质与许多ER蛋白质相互作用，它可能在监测蛋白质通过细胞的转运中起到关键作用。The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER)， and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins， it may play a key role in monitoring protein transport through the cell.关联癌症：结直肠癌。