PCDH18（protocadherin 18），癌症关联基因，基因ID：54510，该基因属于钙粘蛋白原基因家族，属于钙粘蛋白超家族的一个亚家族。该基因编码一种含有6个胞外钙粘蛋白结构域、一个跨膜结构域和一个不同于经典钙粘蛋白的胞质尾的蛋白质。尽管其具体功能尚不明确，但钙黏蛋白相关的神经元受体被认为在大脑特定细胞-细胞连接的建立和功能中发挥作用[由RefSeq提供，2008年7月]This gene belongs to the protocadherin gene family， a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains， a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined， the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain. [provided by RefSeq， Jul 2008]。