NTM(neurotrimin),癌症关联基因,基因ID:50863,该基因编码iglon(lamp,obcam,ntm)家族的一个成员,iglon(lamp,obcam,ntm)家族的免疫球蛋白(ig)结构域含有糖基磷脂酰肌醇(gpi)锚定的细胞粘附分子。编码蛋白可能通过一种亲和力机制促进神经突起的生长和粘附该基因与11号染色体上的一个相关家族成员阿片结合蛋白/细胞粘附分子样(opcml)紧密相连。已发现该基因编码不同亚型的多个转录变体。[由RefSeq提供,2009年1月]This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]。