LCP1(lymphocyte cytosolic protein 1),癌症关联基因,基因ID:3936,质体蛋白是一个肌动蛋白结合蛋白家族,在真核生物进化过程中一直保守,并在高等真核生物的大多数组织中表达。在人类中,发现了两种普遍存在的质体亚型(L和T)质体素1(也称为伞蛋白)是第三种不同的质体亚型,在小肠中高水平表达。L亚型仅在造血细胞系中表达,而T亚型则在具有复制潜能的实体组织的所有其他正常细胞(成纤维细胞、内皮细胞、上皮细胞、黑色素细胞等)中发现。然而,在许多非造血来源的恶性人类细胞中发现了L-质体素,这表明它的表达是在实体组织中诱导肿瘤发生的。[由RefSeq提供,2008年7月]Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found i。