ARAP3（ArfGAP with RhoGAP domain， ankyrin repeat and PH domain 3），癌症关联基因，基因ID：64411，该基因编码一种磷酸肌醇结合蛋白，包含ARF-GAP、RHO-GAP、RAS结合和pleckstrin同源结构域ARF-GAP和RHO-GAP结构域协同介导细胞骨架和细胞形态的重排是一种特异性的PtdIns（3，4，5）P3/PtdIns（3，4）P2刺激的Arf6间隙蛋白已发现该基因的选择性剪接转录本，但其生物学有效性尚未确定[由RefSeq提供，2015年9月]This gene encodes a phosphoinositide binding protein containing ARF-GAP， RHO-GAP， RAS-associating， and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3，4，5)P3/PtdIns(3，4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene， but its biological validity has not been determined. [provided by RefSeq， Sep 2015]。