CBR1（carbonyl reductase 1），癌症关联基因，基因ID：873，由该基因编码的蛋白质属于短链脱氢酶/还原酶（SDR）家族，其功能为NADPH依赖的氧化还原酶，对羰基化合物具有广泛的专一性，例如醌类、前列腺素类和各种外源性化合物。另外，已经发现该基因的剪接转录变体。[由RefSeq提供，2013年11月]The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family， which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds， such as quinones， prostaglandins， and various xenobiotics. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq， Nov 2013]。