二硫辛酸达峰浓度时间为2～4h，口服后生物利用度为87%，食物可减少二硫辛酸吸收。药物在肝脏代谢，有首过效应。经肾排泄，原形药清除半衰期为10～20min。5-(1，2-dithiolan-3-yl)valeric acid; Thiocitic Acid; 1，2-Dithiolane-3-pentanoic acid; 1，2-dithiolane-3-valeric acid; 6，8-thioctic acid; a-lipoic acid; 5-[3-(1，2-dithiolanyl)]pentanoic acid; d-[3-(1，2-dithiacyclopentyl)]pentanoic acid; protogen A; acetate replacing factor; pyruvate oxidation factor; Alpha Lipoic Acid; Lipoic acid