SMARCA1（SWI/SNF related， matrix associated， actin dependent regulator of chromatin， subfamily a， member 1），癌症关联基因，基因ID：6594，这个基因编码swi/snf蛋白家族的一个成员。编码蛋白是一种atp酶，在多种组织中表达，参与转录的染色质重塑复合物。该蛋白还可能在DNA损伤、生长抑制和癌细胞凋亡中发挥作用选择性剪接导致多个转录变体[由RefSeq提供，2013年9月]This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage， growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq， Sep 2013]。