PLCB1（phospholipase C beta 1），癌症关联基因，基因ID：23236，该基因编码的蛋白质催化磷脂酰肌醇4，5-二磷酸形成肌醇1，4，5-三磷酸和二酰甘油这种反应以钙为辅助因子，在许多细胞外信号的细胞内转导中起重要作用。这个基因被两个G蛋白α亚单位α-Q和α-11激活。已经发现了两个编码不同亚型的转录变体。[由RefSeq提供，2008年7月]The protein encoded by this gene catalyzes the formation of inositol 1，4，5-trisphosphate and diacylglycerol from phosphatidylinositol 4，5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits， alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq， Jul 2008]。