Hist1h2al(histone cluster 1, H2al),癌症关联基因,基因ID:667728,组蛋白是真核生物染色体纤维核小体结构的基本核蛋白四个核心组蛋白(H2A、H2B、H3和H4)中的每一个分子形成一个八聚体,其中大约146 bp的DNA被包裹在被称为核小体的重复单元中。连接组蛋白H1在核小体之间与连接DNA相互作用,在染色质压缩成高阶结构中发挥作用这个基因是在13号染色体上发现的一个组蛋白假基因。[由RefSeq提供,2015年10月]Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is a histone pseudogene found on chromosome 13. [provided by RefSeq, Oct 2015]。