NKX3-1（NK3 homeobox 1），癌症关联基因，基因ID：4824，这个基因编码一个含有转录因子的同源盒。这种转录因子在前列腺组织中作为上皮细胞生长的负调节因子。该基因的异常表达与前列腺癌的进展有关。交替剪接导致该基因的多个转录变体。[由RefSeq提供，2012年1月]This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq， Jan 2012]。