IL6R（interleukin 6 receptor），癌症关联基因，基因ID：3570，这个基因编码白细胞介素6（IL6）受体复合物的一个亚单位。白细胞介素6是一种有效的多效性细胞因子，调节细胞生长和分化，在免疫应答中发挥重要作用。il6受体是一种由该蛋白和白细胞介素6信号转导子（il6st/gp130/il6β）组成的蛋白质复合物，也是许多其他细胞因子共有的受体亚单位。il6及其受体的异常表达与多发性骨髓瘤、自身免疫性疾病、前列腺癌等多种疾病的发病有关。另外，已经报道了编码不同亚型的剪接转录变体。在9号染色体上发现了该基因的假基因。[由RefSeq提供，2011年5月]This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta)， a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases， such as multiple myeloma， autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. 。