SDHC（succinate dehydrogenase complex subunit C），癌症关联基因，基因ID：6391，这个基因编码四个核编码亚单位之一，包括琥珀酸脱氢酶，也被称为线粒体复合物ii，一个三羧酸循环和线粒体有氧呼吸链的关键酶复合物。编码的蛋白质是两个完整的膜蛋白之一，它们将复合物的其他亚单位（形成催化核心）固定在线粒体内膜上。这个基因在不同染色体上有几个相关的假基因。这个基因的突变与副神经节瘤有关。另外，已经描述了剪接转录变体。[由RefSeq提供，2013年5月]This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase， also known as mitochondrial complex II， a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex， which form the catalytic core， to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described. [provided by RefSeq， May 2013]。