PPP2R1A（protein phosphatase 2 scaffold subunit Aalpha），癌症关联基因，基因ID：5518，该基因编码蛋白质磷酸酶2的恒定调节亚单位。蛋白磷酸酶2是四种主要的ser/thr磷酸酶之一，与细胞生长和分裂的负调控有关。它由一种常见的异聚核心酶组成，由一个催化亚基和一个恒定的调节亚基组成，与多种调节亚基相结合。恒定调节亚基a充当支架分子，以协调催化亚基和可变调节b亚基的组装。该基因编码恒定调节亚单位a的α亚型。已描述了选择性剪接的转录变体。[由RefSeq提供，2010年4月]This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases， and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme， which is composed of a catalytic subunit and a constant regulatory subunit， that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been describ。