LZTR1(leucine-zipper-like transcription regulator 1),癌症关联基因,基因ID:8216,这个基因编码一个btb-kelch超家族成员。最初被描述为一种基于与碱性亮氨酸拉链样家族成员弱同源性的假定转录调节器,随后编码的蛋白质被证明仅局限于高尔基网络,在那里它可能有助于稳定高尔基复合体。该基因缺失可能与Digeorge综合征有关。This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.关联癌症:神经鞘瘤病。