CSF3R（colony stimulating factor 3 receptor），癌症关联基因，基因ID：1441，该基因编码的蛋白质是集落刺激因子3的受体，集落刺激因子3是一种控制粒细胞产生、分化和功能的细胞因子。编码蛋白是细胞因子受体家族的一员，也可能在某些细胞表面粘附或识别过程中发挥作用。另外，还描述了拼接转录变体。这种基因的突变是导致Kostmann综合征的原因，也被称为严重先天性中性粒细胞减少症。The protein encoded by this gene is the receptor for colony stimulating factor 3， a cytokine that controls the production， differentiation， and function of granulocytes. The encoded protein， which is a member of the family of cytokine receptors， may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome， also known as severe congenital neutropenia.关联癌症：非典型慢性粒细胞白血病，慢性中性粒细胞白血病。关联化疗药物：芦可替尼/鲁索利替尼/鲁索替尼。