TSC1（tuberous sclerosis 1），癌症关联基因，基因ID：7248，该基因编码一种生长抑制蛋白，被认为在稳定块茎素中起作用。这种基因的突变与结节性硬化症有关。选择性剪接导致多个转录变体。This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.关联癌症：膀胱癌，浸润性膀胱移行细胞癌，非小细胞肺癌，肾细胞癌，结节性硬化症。关联化疗药物：依维莫司，MTOR Inhibitors，替西罗莫司/坦西莫司。