自磷酸化

当配体-受体结合时，受体胞外结构域构象变化导致相邻的单跨膜受体二聚化，以利于受体间的交互磷酸化,即自磷酸化。含义:1. it carried phosphate groups attached covalently to one or more of its amino acid side chains 2. it served as a substrate for phosphorylation by a protein kinase 同时可以提供磷酸集团，和作为蛋白质激酶磷酸化的底物