ZMYM3(zinc finger MYM-type containing 3),癌症关联基因,基因ID:9203,该基因位于x染色体上,并受到x失活的影响。它在脊椎动物中高度保守,在大脑中表达最丰富。编码蛋白是组蛋白脱乙酰酶的一个组成部分,含有多蛋白复合物,通过改变染色质结构来保持基因沉默。涉及该基因的染色体易位(x;13)与x连锁认知障碍有关。已经发现了该基因的几种选择性剪接转录变体。[由RefSeq提供,2010年1月]This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]。