USP48（ubiquitin specific peptidase 48），癌症关联基因，基因ID：84196，该基因编码一个蛋白质结构域，该结构域与肽酶家族C19（也称为泛素羧基末端水解酶家族2）相关联家族成员作为脱双歧酶，识别和水解泛素c端甘氨酸的肽键。肽酶家族c19中的酶参与了多泛素前体和泛素化蛋白的加工。交替转录剪接变体，编码不同的亚型，已经被描述出来。[由RefSeq提供，2008年7月]This gene encodes a protein containing domains that associate it with the peptidase family C19， also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes， recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants， encoding different isoforms， have been characterized. [provided by RefSeq， Jul 2008]。