TBL3（transducin beta like 3），癌症关联基因，基因ID：10607，由该基因编码的蛋白质与含有wd40重复序列的蛋白质家族成员具有序列相似性。WD40是一个蛋白质大家族，似乎具有调节功能wd40重复序列介导蛋白质与蛋白质的相互作用，其家族成员参与信号转导、rna处理、基因调控、囊泡转运、细胞骨架组装等过程，可能在细胞类型分化的调控中发挥作用。该基因有多个聚腺苷酸化位点。它可能有多个选择性剪接的转录变体，但这些变体尚未完全描述。[由RefSeq提供，2008年7月]The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins， which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction， RNA processing， gene regulation， vesicular trafficking， cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. [provided by RefSeq， Jul 2008]。