PURA（purine rich element binding protein A），癌症关联基因，基因ID：5813，这种基因产物是一种序列特异的单链dna结合蛋白。它优先与富含嘌呤元素PUR的单链结合，PUR存在于从酵母到人类的各种真核生物的复制起源和基因侧翼区域因此，它参与了dna复制和转录的控制。该基因缺失与骨髓增生异常综合征和急性髓性白血病有关。[由RefSeq提供，2008年7月]This gene product is a sequence-specific， single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR， which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus， it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq， Jul 2008]。