NLRC3（NLR family CARD domain containing 3），癌症关联基因，基因ID：197358，这个基因编码一个NOD样受体家族成员编码蛋白是先天免疫的胞质调节因子。该蛋白直接与干扰素基因刺激因子（sting）相互作用，以防止其适当的转运，导致sting依赖性激活的先天免疫反应中断。选择性剪接导致多个转录变体[由RefSeq提供，2014年2月]This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING)， to prevent its proper trafficking， resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq， Feb 2014]。