MS4A3(membrane spanning 4-domains A3),癌症关联基因,基因ID:932,这个基因编码一个跨膜4a基因家族的成员。该蛋白家族成员具有共同的结构特征和相似的内含子/外显子剪接边界,在造血细胞和非淋巴组织中表现出独特的表达模式。该家族成员可能在信号转导中发挥作用,并可能作为与受体复合物相关联的亚单位发挥作用。编码这种蛋白质的基因定位于11q12,在一组相关的家族成员中。选择性剪接可能导致多个转录变异体;然而,并非所有变异体都已被完全描述。[由RefSeq提供,2008年7月]This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]。