MUC5B（mucin 5B， oligomeric mucus/gel-forming），癌症关联基因，基因ID：727897，该基因编码粘液蛋白家族的一个成员，它是粘液分泌中高度糖基化的大分子成分。这个家族成员是黏液中主要的凝胶形成粘蛋白对唾液、正常肺粘液和宫颈粘液的润滑和粘弹性有重要影响该基因在慢性鼻窦炎（CRS）、鼻息肉病（CRS）、慢性阻塞性肺病（COPD）和幽门螺杆菌相关性胃病（H.pylori-associated gastrial disease）等人类疾病中表达上调，可能与这些疾病的发病机制有关[由RefSeq提供，2010年7月]This gene encodes a member of the mucin family of proteins， which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva， normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases， including sinus mucosa of chronic rhinosinusitis (CRS)， CRS with nasal polyposis， chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease， and it may be involved in the pathogenesis of these diseases. [provided by RefSeq， Jul 2010]。