DDX5（DEAD-box helicase 5），癌症关联基因，基因ID：1655，这个基因编码rna解旋酶死盒家族的一个成员，由于其作为衔接分子的作用，参与多种细胞过程，促进与大量其他因素的相互作用。该蛋白参与包括RNA结构改变、作为转录的共同调节者、剪接的调节者以及小的非编码RNA的加工的途径这个家族的成员包含9个保守的基序，包括保守的asp glu ala asp（dead）基序，对atp结合和水解以及rna结合和解旋活动都很重要。这种基因的失调可能在癌症的发展中起作用选择性剪接导致多个转录变体[由RefSeq提供，2017年9月]This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule， promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures， plays a role as a coregulator of transcription， a regulator of splicing， and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs， including the conserved Asp-Glu-Ala-Asp (DEAD) motif， important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in 。