ABCC11(ATP binding cassette subfamily C member 11),癌症关联基因,基因ID:85320,该基因编码的蛋白质是atp结合盒(abc)转运蛋白超家族的成员。abc蛋白通过细胞外和细胞内的膜运输各种分子。ABC基因分为七个不同的亚家族(ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White)ABC全转运蛋白是MRP亚家族的一员,参与多药耐药该基因的产物参与胆汁酸、结合类固醇和环核苷酸的生理过程。此外,该基因中的一个单核苷酸多态性(snp)负责确定人类耳垢的类型。这个基因和家族成员ABCC12被确定是通过复制获得的,并且都定位在染色体16q12.1上已经描述了该基因的多个选择性剪接转录变体。[由RefSeq提供,2008年7月]The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of hum。