TRAF7（TNF receptor associated factor 7），癌症关联基因，基因ID：84231，肿瘤坏死因子（TNF；见MIM 191160）受体相关因子，如TRAF7，是TNF受体超家族成员的信号转导因子（见MIM 191190）。trafs由一个富含n-末端半胱氨酸/组氨酸的区域组成，该区域含有锌环和/或锌指基序；一个卷曲的线圈（亮氨酸拉链）基序；以及一个定义traf家族的同源区域，traf域，其参与自缔合和受体结合。[由omim提供，2004年4月]Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors， such as TRAF7， are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family， the TRAF domain， which is involved in self-association and receptor binding.[supplied by OMIM， Apr 2004]。