SLX4(SLX4 structure-specific endonuclease subunit),癌症关联基因,基因ID:84464,该基因编码一种蛋白质,作为多结构特异性核酸内切酶的组装成分。这些核酸内切酶复合物对于修复特定类型的dna损伤是必需的,对于细胞对复制分叉失败的反应也是至关重要的。在范科尼贫血患者中发现该基因突变。[由RefSeq提供,2016年9月]This gene encodes a protein that functions as an assembly component of multiple structure-specific endonucleases. These endonuclease complexes are required for repair of specific types of DNA lesions and critical for cellular responses to replication fork failure. Mutations in this gene were found in patients with Fanconi anemia. [provided by RefSeq, Sep 2016]。