RAC2（Rac family small GTPase 2），癌症关联基因，基因ID：5880，该基因编码小鸟苷三磷酸（gtp）代谢蛋白ras超家族的一个成员。编码的蛋白质定位于质膜，在质膜上调节各种过程，如分泌、吞噬和细胞极化。这种蛋白质的活性也与活性氧的产生有关。该基因突变与中性粒细胞免疫缺陷综合征有关。这个基因在第6号染色体上有一个假基因。[由RefSeq提供，2013年7月]This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane， where it regulates diverse processes， such as secretion， phagocytosis， and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq， Jul 2013]。