NFE2L3（nuclear factor， erythroid 2 like 3），癌症关联基因，基因ID：9603，该基因编码转录因子cap'n'领碱性区亮氨酸拉链家族的一个成员。编码的蛋白质异源二聚体与小肌肉腱膜纤维肉瘤因子结合目标基因中的抗氧化反应元件。该蛋白是一种膜结合糖蛋白，靶向内质网和核膜。这个基因的假基因存在于16、17和18号染色体上。[由RefSeq提供，2009年3月]This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16， 17， and 18. [provided by RefSeq， Mar 2009]。