IGF1(insulin like growth factor 1),癌症关联基因,基因ID:3479,该基因编码的蛋白质在功能和结构上与胰岛素相似,是一个参与调节生长发育的蛋白质家族的成员。编码的蛋白质由一个前体加工而成,由一个特定的受体结合并分泌。该基因缺陷是胰岛素样生长因子i缺乏的原因之一。选择性剪接导致编码不同亚型的多个转录变体,这些亚型可能经过类似的处理以生成成熟蛋白质。[由RefSeq提供,2015年9月]The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]。