NTHL1（nth like DNA glycosylase 1），癌症关联基因，基因ID：4913，这个基因编码的蛋白质是一种核酸内切酶iii家族的dna n-糖基化酶。与大肠杆菌中的类似蛋白质一样，编码的蛋白质在含有氧化嘧啶残基的dna底物上具有dna糖苷酶活性，并且具有无嘌呤/无嘧啶裂解酶活性。[由RefSeq提供，2008年10月]The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli， the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. [provided by RefSeq， Oct 2008]。