SOX9（SRY-box transcription factor 9），癌症关联基因，基因ID：6662，该基因编码的蛋白质与hmg盒类dna结合蛋白的其他成员一起识别ccttgag序列。它在软骨细胞分化过程中起作用，并与类固醇生成因子1一起调节抗米勒氏激素（amh）基因的转录。缺陷导致骨骼畸形综合征-畸形-畸形-畸形，常伴性反转。[由RefSeq提供，2008年7月]The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and， with steroidogenic factor 1， regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia， frequently with sex reversal. [provided by RefSeq， Jul 2008]。