HSD3B1（hydroxy-delta-5-steroid dehydrogenase， 3 beta- and steroid delta-isomerase 1），癌症关联基因，基因ID：3283，这个基因编码的蛋白质是一种酶，催化delta-5-3-β-羟基类固醇前体氧化转化为delta-4-酮类固醇，从而产生所有种类的类固醇激素。编码蛋白还催化3-β-羟基和3-酮-5-α-雄甾烷类固醇的相互转化。[由RefSeq提供，2016年6月]The protein encoded by this gene is an enzyme that catalyzes the oxidative conversion of delta-5-3-beta-hydroxysteroid precursors into delta-4-ketosteroids， which leads to the production of all classes of steroid hormones. The encoded protein also catalyzes the interconversion of 3-beta-hydroxy- and 3-keto-5-alpha-androstane steroids. [provided by RefSeq， Jun 2016]。