TMEM127（transmembrane protein 127），癌症关联基因，基因ID：55654，这个基因编码一个跨膜蛋白和3个预测的跨膜结构域。该蛋白与早期内质体结构对应的泡状细胞器亚群、高尔基体和溶酶体相关，并可能参与这些结构之间的蛋白质运输。这个基因和其他几个基因的突变导致嗜铬细胞瘤。另外，编码相同蛋白质的剪接转录变体已经被鉴定。[由RefSeq提供，2010年8月]This gene encodes a transmembrane protein with 3 predicted transmembrane domains. The protein is associated with a subpopulation of vesicular organelles corresponding to early endosomal structures， with the Golgi， and with lysosomes， and may participate in protein trafficking between these structures. Mutations in this gene and several other genes cause pheochromocytomas. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq， Aug 2010]。