PARP3（poly(ADP-ribose) polymerase family member 3），癌症关联基因，基因ID：10039，这个基因编码的蛋白质属于parp家族。这些酶通过聚adp核糖化修饰核蛋白，这是dna修复、细胞凋亡调节和维持基因组稳定性所必需的。该基因编码聚腺苷二磷酸核糖转移酶3，在整个细胞周期中优先定位于子中心粒。另外，还发现了编码不同亚型的剪接转录变体。[由RefSeq提供，2008年7月]The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation， which is required for DNA repair， regulation of apoptosis， and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3， which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq， Jul 2008]。