C8orf34（chromosome 8 open reading frame 34），癌症关联基因，基因ID：116328，该基因编码与环状AMP依赖性蛋白激酶调节剂有关的蛋白。 在接受化学治疗的患者中，该基因的天然突变与发生严重毒性反应的风险增加有关，例如腹泻和中性粒细胞减少。 [由RefSeq提供，2017年3月]This gene encodes a protein that is related to the cyclic AMP dependent protein kinase regulators. Naturally occurring mutations in this gene are associated with an increased risk for severe toxicities， such as diarrhea and neutropenia， in patients undergoing chemotherapeutic treatment. [provided by RefSeq， Mar 2017]。