JUN（Jun proto-oncogene， AP-1 transcription factor subunit），癌症关联基因，基因ID：3725，该基因是禽肉瘤病毒17的假定转化基因。它编码一种与病毒蛋白高度相似的蛋白质，并与特定靶DNA序列直接相互作用以调节基因表达。这个基因是无内含子的，被定位到1P32-P31，一个涉及人类恶性肿瘤易位和缺失的染色体区域。This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein， and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31， a chromosomal region involved in both translocations and deletions in human malignancies.关联癌症：结直肠癌。关联化疗药物：厄贝沙坦。