ASNS(asparagine synthetase (glutamine-hydrolyzing)),癌症关联基因,基因ID:440,这个基因编码的蛋白质参与天冬酰胺的合成。这个基因补充了温度敏感型仓鼠突变体TS11的突变,该突变体在非耐受温度下阻止细胞周期G1期的进展。另外,还描述了该基因的剪接转录变体。The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene.关联癌症:卵巢癌,T细胞白血病。关联化疗药物:L-门冬酰胺酶。