PALB2（partner and localizer of BRCA2），癌症关联基因，基因ID：79728，这个基因编码一种可能抑制肿瘤的蛋白质。这种蛋白与乳腺癌2早发蛋白（BRCA2）在核病灶结合并与之共定位，可能允许BRCA2稳定的核内定位和积累。This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.关联癌症：乳腺癌，胰腺癌，前列腺癌。关联化疗药物：丝裂霉素C，奥拉帕利，奥拉帕尼。