REV3L(REV3 like, DNA directed polymerase zeta catalytic subunit),癌症关联基因,基因ID:5980,这个基因编码的蛋白质代表了dna聚合酶zeta的催化亚单位,它在易位dna合成中起作用。编码的蛋白质可以在线粒体中找到,在那里它可以保护dna免受损伤。这个基因的缺陷是mobius综合征的一个原因。[由RefSeq提供,2017年1月]The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome. [provided by RefSeq, Jan 2017]。